Online First Nr133

Psychiatr. Pol. ONLINE FIRST Nr 133: 1–11

Published ahead of print 25 March 2019

DOI: https://doi.org/10.12740/PP/OnlineFirst/104445

Adrian Andrzej Chrobak, Bartosz Bohaterewicz, Anna Tereszko,
Anna Krupa, Anna Sobczak, Anna Ceglarek, Magdalena Wielgus,
Magdalena Fafrowicz, Marcin Siwek, Amira Bryll, Tadeusz Marek,
Dominika Dudek

FREE POLISH FULLTEXT:
Zaburzenia połączeń funkcjonalnych między czołowymi polami okoruchowymi, wzgórzem a móżdżkiem w chorobie afektywnej dwubiegunowej
 
Summary
Objectives: The aim of our study is to evaluate functional connectivity of cerebellothalamo- cortical networks linking frontal eye fields (FEF) and cerebellar regions associated with oculomotor control: nodulus (X), uvula (IX), flocculus (H X) and ventral paraflocculus (H IX) in bipolar disorder (BD) with the use of resting state functional magnetic resonance imaging (rsfMRI).
Methods: 19 euthymic BD patients and 14 healthy controls underwent rsfMRI examination. Functional connectivity between bilateral FEF, thalamus and cerebellar regions associated with oculomotor control was evaluated.
Results: BD patients revealed decreased functional connectivity between following structures: right FEF and bilateral thalamus, flocculus (H X), uvula (IX); right thalamus and right FEF; between right flocculus (H X) and right FEF, left thalamus; between left thalamus and bilateral FEF and right flocculus (H X).
Conclusions: BD patients presented decreased functional connectivity among FEF, thalamus and cerebellar structures associated with eye movements control. Oculomotor evaluation of BD patients assessed with rsfMRI may help to determine whether altered functional connectivity observed in our study is associated with eye movements deficits in BD.
 

ISSN 0033-2674 (PRINT)

ISSN 2391-5854 (ONLINE)


Psychiatria Polska
is an Open Access journal:
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Zadanie finansowane
w ramach umowy
nr 739/P-DUN/2018
ze środków MNiSW
przeznaczonych
na działalność
upowszechniającą naukę



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