435–446____

Psychiatr. Pol. 2021; 55(2): 435–446

 

Sebastian Masternak, Olga Padała, Hanna Karakuła-Juchnowicz
 

FREE POLISH FULLTEXT:
 

FREE ENGLISH FULLTEXT:
False-positive drug test results in patients taking psychotropic drugs. A literature review

Summary
Aim. The study reviews the literature on false-positive drug test results in patients taking psychotropic medications.
Method. A narrative review of available literature in English and Polish was conducted by searching MEDLINE/PubMed and Google Scholar databases using the search phrase ‛falsepositive drug test’ and names of selected registered antidepressant, antipsychotic and mood stabilizing medications as well as pharmaceuticals used in the treatment of ADHD. Review articles, case reports and original papers from years 1990–2019 were analyzed.
Results. False-positive drug test results have been reported for many psychiatric drugs: clomipramine, amitriptyline, bupropion, trazodone, sertraline, venlafaxine, hydroxyzine, haloperidol, sulpiride, perazine, levomepromazine, aripiprazole, risperidone, amisulpride, quetiapine, lamotrigine, carbamazepine, methylphenidate, and atomoxetine. No such reports have been found for other drugs considered in this study.
Conclusions. When interpreting urine drug tests, caution should be exercised, especially when the tested person categorically denies the use of psychoactive substances. In such situations, the patient’s medication list should be analyzed to ascertain that the obtained result is not false-positive. When test results are unclear, the presence of drugs in the urine can be effectively confirmed or excluded using gas chromatography. Unfortunately, most of the data available in the literature are case reports, which means they require further support from studies of large cohorts of patients taking psychotropic medications.



ISSN 0033-2674 (PRINT)

ISSN 2391-5854 (ONLINE)


Psychiatria Polska
is an Open Access journal:
Creative Commons: CC-BY
SHERPA RoMEO:
Blue


Zadanie finansowane
w ramach umowy
nr 739/P-DUN/2018
ze środków MNiSW
przeznaczonych
na działalność
upowszechniającą naukę


KRW PTP dziękuje 
firmie PPL – Koral – J.Koral sp.j.
za wsparcie finansowe 
udzielone w 2020 roku




Inne strony PTP:
Other PTP websites:

www.psychiatria.org.pl
www.psychiatriapsychoterapia.pl

www.archivespp.pl
www.psychoterapiaptp.pl

Psychiatria Polska
INDEXED IN:
Thomson Reuters Master List
Science Citation Index Expanded
Journal Citation Reports
(Impact Factor 1,190)

Medline/Index Medicus
PubMed/LinkOut
MNiSW (40 pkt)
Scopus/SCImago
(SJR 0,381; SNIP 0,587)
EMBASE/Excerpta Medica
PsycINFO, EBSCO,
Index Copernicus
Erih Plus, Cochrane Library
CrossRef/DOI

We recommend:

Pharmacological Reports

 


KONTAKT Z REDAKCJĄ - wyłącznie e-mail: redakcja@psychiatriapolska.pl 

Biuro KRW PTP - prenumeraty, faktury:  518-330-994 lub biuro@krwptp.pl 
krwptp.pl