The article, based on the literature review, presents actual concerns on prognosis and opportunity to achieve recovery in persons with schizophrenia. Catamnestic long-term studies published during last decades more often indicated a favorable course of schizophrenia than it was in the past. One explanation may be the progress in pharmacotherapy, which allows the achievement of a better outcome in the treatment. On the other hand, the researchers have been committed to more detailed studies on the course of schizophrenia by more frequently repeated public testimonials of the ill persons, which forced the prognosis to be more optimistic. A good example is the discussion about the recovery in schizophrenia and the change in perception of the disease, despite differences in the attitudes between clinicians and patients. Seeing the opportunity to conduct a normal life in spite of serious mental disease is challenging for patients and their relatives, as well for psychiatrists and therapists. It motivates to overcome the limitations that the disease brings and the barriers in society.