Aim. Assessment of body image satisfaction, sense of coherence and life satisfaction during the therapy of women with transsexualism. Methods. 27 women with transsexualism (before therapy - 9; in therapy but before surgery - 7; after surgery - 11), in different stages of therapy and 15 women and 15 men from the control group participated in the study. The Body Image Scale, the Sense of Coherence-SOC 29 and Satisfaction with Life Scale - SWLS. Results and conclusions. The results suggest that the increased satisfaction from the body image in the group of women with transsexualism is related with progress in therapy. Persons from the control group were significantly more satisfied form their own body image than persons with transexualism. The progress of therapy is related with the decrease of will to change the body. The mean scores on the meaningfulness subscale of Sense of Coherence Scale was significantly lower in the group of patients before the beginning of treatment than in the control group and in the group after surgery. There was no relation between the level of life satisfaction and stages of therapy.