Enantiomers: a new issue in pharmacotherapy of depression?

Enantiomers as the drug forms being optically active have currently a considerable influence in most pharmacotherapy areas. They have aroused a large interest in the field of psychiatry and especially for treatment of depression. This is due to the fact that enantiomers (chiral forms) of many drugs may have different pharmacokinetic, pharmacological or pharmacogenetic profiles. Therefore, in many cases, the use of a single drug enantiomer might have had huge advantage over previously used forms and lead to strong improvement in current treatment. The stereoselective property of fluoxetine being such psychotropic drug is an example that belongs to the group of selective serotonin reuptake inhibitors (SSRIs).

eISSN:	2391-5854
ISSN:	0033-2674