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Industry-corrupted psychiatric trials
 
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1
Depression Research Unit, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
 
2
Department of Philosophy, California State University, Northridge, California
 
3
Critical and Ethical Mental Health Research Group, Robinson Research Institute, University of Adelaide, Australia
 
 
Submission date: 2017-10-07
 
 
Final revision date: 2017-11-11
 
 
Acceptance date: 2017-11-11
 
 
Online publication date: 2017-12-30
 
 
Publication date: 2017-12-30
 
 
Psychiatr Pol 2017;51(6):993-1008
 
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ABSTRACT
The goal of this paper is to expose the research misconduct of pharmaceutical industry sponsored clinical trials via three short case studies of corrupted psychiatric trials that were conducted in the United States. We discuss the common elements that enable the misrepresentation of clinical trial results including ghostwriting for medical journals, the role of key opinion leaders as co-conspirators with the pharmaceutical industry and the complicity of top medical journals in failing to uphold standards of science and peer review. We conclude that the corruption of industry-sponsored clinical trials is one of the major obstacles facing evidence-based medicine.
eISSN:2391-5854
ISSN:0033-2674
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